U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07600814) titled 'Pain Induced by m-Cresol as Preservative' on May 15.
Brief Summary: Preservatives such as m-Cresol are essential components in many subcutaneously injected medications, including insulin or human growth hormone, to prevent bacterial growth. However, clinical reports have suggested that these preservatives may cause local discomfort or pain at the injection site, which can negatively impact treatment adherence. While m-Cresol is widely used, its direct contribution to injection-site pain has not yet been investigated in a prospective clinical trial.
This study aims to investigate whether subcutaneous injection of m-Cresol at concentr...