Clinical Trial: Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression

U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07750938) titled 'Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression' on July 26.

Brief Summary: Background:

Helicobacter pylori (H. pylori) infection affects approximately 50% of the global population and is closely associated with chronic gastritis, peptic ulcer disease, and gastric cancer. Eradication of H. pylori can reduce the overall risk of gastric cancer by 39%. Current international guidelines recommend bismuth-containing quadruple therapy as first-line treatment; however, its complex regimen, adverse effects, cost, and suboptimal patient adherence limit its clinical application. Potent acid suppression is essential ...