U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07769567) titled 'Optimization of Therapeutic Drug Monitoring in Pediatric Kidney Transplant' on Aug. 13.
Brief Summary: The goal of this observational, pharmacokinetic study is to evaluate factors that change drug exposure in pediatric kidney transplant recipients so we can make better dosing decisions. The main question it aims to answer is:
Can we quantify the impact of factors that change with time (like food intake and medication adherence) on tacrolimus and mycophenolate? Our hypothesis is that inconsistent drug and food intake will increase day to day variability in drug exposure, and we can use this information to help us make decisions abou...