U.S., April 8 -- ClinicalTrials.gov registry received information related to the study (NCT07514507) titled 'Optimization of Melatonin Administration in Healthy Adults' on Dec. 22, 2025.
Brief Summary: The goal of this clinical trial is to evaluate whether the timing and dosage of exogenous melatonin can improve sleep onset and maintenance in healthy adults aged 18-45 years (50% female) with no history of sleep disorders.
The main questions it aims to answer is whether an optimized melatonin administration schedule (4 mg, 3 hours before bedtime) will be more effective in improving sleep initiation and maintenance than an administration schedule more commonly advised (2 mg, 30 minutes before bedtime).
Researchers will compare five conditi...