U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07438964) titled 'Non-invasive Brain Stimulation in Multiple Sclerosis Fatigue' on Feb. 12.
Brief Summary: The neurobiological basis of central fatigue in multiple sclerosis remained unclear so far. This study investigates reward-related brain mechanisms, inflammation, and their modulation by non-invasive brain stimulation using fMRI, proteomics, and clinical measures to improve future treatment of central fatigue in MS. In the study, persons suffering from relapsing-remitting MS (RRMS) with vs. without comorbid central fatigue will be included.
The study comprises five experimental visits conducted at Charite University Medicine on five consecutive...