U.S., May 2 -- ClinicalTrials.gov registry received information related to the study (NCT07561437) titled 'NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors' on April 22.
Brief Summary: Study Population: Adult subjects aged 18-75 years with relapsed/refractory advanced solid tumors (including liver, gastric, colorectal, ovarian cancer, etc.) and malignant ascites confirmed by cytology, who have failed at least 2 lines of standard systemic therapy.
Study Design: This is a dose-escalation, single-center, open-label, prospective Phase 1 study. A total of 18 subjects will be enrolled and assigned to 2 administration groups (9 subjects each):
Group A (Intravenous infusion): For subjects with small-volume malign...