Clinical Trial: NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices

U.S., Sept. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07806149) titled 'NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices' on Sept. 03.

Brief Summary: This is an early study of a catheter-based minimally invasive procedure called SESAME to slice thick heart muscle as described below.

Excessively-thick heart muscle can cause serious heart disease, especially heart failure with preserved ejection fraction, which causes shortness of breath and heart failure symptoms such as edema (swelling) and pulmonary congestion (lung water). Specific circumstances of excessively-thick heart muscle can block outflow of blood from the main heart pum...