U.S., June 6 -- ClinicalTrials.gov registry received information related to the study (NCT07629635) titled 'Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy' on May 22.

Brief Summary: Migraine is a common and often disabling condition, but its exact causes are not fully understood. Some people with migraines have a small opening in the heart wall called a patent foramen ovale (PFO). In some of these patients, closing this opening or taking a medication that inhibits blood platelets (prasugrel) has been shown to reduce migraines. However, not everyone benefits, and it is unclear why. This study is being done to better understand whether closing a PFO can provide lasting migraine relief - especially in patients whose...