Clinical Trial: Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in PAH.

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07751120) titled 'Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in PAH.' on July 30.

Brief Summary: This pilot clinical trial analysis will evaluate the initial safety, feasibility, and pharmacokinetics of microbiota transplant therapy (MTT) with antibiotic pre-conditioning and fiber supplementation vs. placebo in patients with pulmonary arterial hypertension (PAH). This trial will inform development of future trials of MTT as a treatment for PAH. 24 PAH patients will be randomized to receive either MTT with antibiotic preconditioning + fiber supplementation, MTT with antibiotic preconditioning + placebo supplementati...