Clinical Trial: Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening

U.S., June 9 -- ClinicalTrials.gov registry received information related to the study (NCT07631624) titled 'Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening' on May 04.

Brief Summary: The MET-SELS study aims to revolutionize how we identify individuals for lung cancer screening by moving beyond the limitations of self-reported smoking history. Currently, eligibility for low-dose CT (LDCT) scans relies on "pack-years"-a metric often compromised by recall bias, under-reporting, and an inability to account for the biological nuances of smoke inhalation or environmental exposure. Consequently, current criteria miss nearly half of incidental lung cancers.

To bridge this gap, the study investigates ...