U.S., March 31 -- ClinicalTrials.gov registry received information related to the study (NCT07501507) titled 'Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments' on Dec. 01, 2025.

Brief Summary: Randomized study comparing the structural efficacy of methotrexate versus placebo in digital osteoarthritis

Study Start Date: May 02

Study Type: INTERVENTIONAL

Condition: Erosive Hand Osteoarthritis

Intervention: DRUG: Methotrexate Injectable Solution

Injection of methotrexate every week during 12 month

DRUG: Placebo

The placebo consists of a 0.9% solution of sodium chloride (NaCl) in sterile distilled water for injection. This solution was chosen as the placebo. Injection every week during 12 month.

Recruitment ...