U.S., Jan. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07353788) titled 'Mechanical Power in One-lung Ventilation' on Dec. 09, 2025.
Brief Summary: Thoracic surgery usually necessitates one-lung ventilation (OLV) to provide surgical access while maintaining adequate gas exchange. However, OLV is associated with an increased risk of PPCs , a major cause of morbidity and mortality. Mechanical power, a composite parameter incorporating tidal volume, respiratory rate, driving pressure, and flow resistance, has been proposed as a key factor influencing ventilator-induced lung injury (VILI) and postoperative outcome. Understanding the association between mechanical power during OLV and PPCs could provide insig...