Clinical Trial: Luminal Bladder Cancer Effective Response to Neoadjuvant Chemotherapy (LUMBER-NAC)

U.S., Aug. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07762586) titled 'Luminal Bladder Cancer Effective Response to Neoadjuvant Chemotherapy (LUMBER-NAC)' on May 01.

Brief Summary: This study is a two-arm phase II randomized trial investigating patients with luminal subtype muscle-invasive bladder cancer (MIBC) receiving neoadjuvant therapy (NAT) followed by cystectomy compared to those receiving upfront cystectomy.

Study Start Date: July 10

Study Type: INTERVENTIONAL

Condition: Bladder Cancer

Intervention: DRUG: Neoadjuvant Therapy

Patients will undergo standard of care neoadjuvant therapy followed by radical cystectomy

PROCEDURE: Upfront radical cystectomy

Patients will undergo upfront radic...