Clinical Trial: Long-term Anticoagulation in a Patient With Severe Hemophilia A

U.S., Jan. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07314983) titled 'Long-term Anticoagulation in a Patient With Severe Hemophilia A' on Sept. 22, 2025.

Brief Summary: To date, and to our knowledge, no case of severe hemophilia A patients receiving long-term anticoagulation has been published. Severe hemophilia A is a hereditary bleeding disorder characterized by a factor VIII (FVIII) deficiency of <1%. Anticoagulation remains a real challenge in these patients, given the precarious hemostatic balance between the bleeding risk associated with anticoagulation and the antithrombotic protection associated with factor VIII deficiency. The advent of new replacement therapies, characterized by FVIII molecul...