U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT07588295) titled 'Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease' on April 28.
Brief Summary: Numerous clinical studies have highlighted the role of macrophages in the destabilization of coronary lesions; however, there is limited literature on the relationship between circulating monocytes and intraplaque macrophages.
This study aims to evaluate and compare the presence of macrophages and their subsequent activation within coronary and peripheral atherosclerotic lesions, and to correlate these findings with the distribution of circulating monocyte subpopulations.
Study Start Date: March 18, 2024
Study Type: INTE...