U.S., Sept. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07838246) titled 'Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch Syndrome' on Sept. 11.
Brief Summary: Lynch syndrome (LS) is an autosomal dominant hereditary condition that markedly increases the risk of colorectal cancer (CRC) and other malignancies. Standard surveillance relies on colonoscopy every 1-2 years starting at age 20-25 years, an invasive and costly procedure that may become burdensome during lifelong follow-up and may miss interval cancers. This prospective, single-institution, observational study aims to identify minimally invasive plasma, stool, and urine biomarkers that could improve the detection of early colorectal ...