Clinical Trial: Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV

U.S., June 12 -- ClinicalTrials.gov registry received information related to the study (NCT07640880) titled 'Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV' on May 31.

Brief Summary: Metabolic dysfunction-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, is increasingly prevalent worldwide. People living with HIV (PWH) face a higher risk of developing MASLD due to chronic immune activation and long-term antiretroviral therapy, yet whether the underlying biological changes differ from those in HIV-negative individuals with MASLD remains unknown.

This prospective observational study will enroll three groups: PWH with MASLD, HIV-negative individuals with MASLD, and h...