Clinical Trial: Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07605858) titled 'Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep' on Jan. 21.

Brief Summary: Interactions between epilepsy and sleep are numerous and bidirectional. Sleep can facilitate epileptic activity and seizures in several syndromes, while sleep deprivation increases cortical excitability and seizure susceptibility. Conversely, sleep disturbances are highly prevalent in patients with epilepsy (PWE).

Using simultaneous stereoelectroencephalography (SEEG)-polysomnography, the investigators previously showed that sleep fragmentation in focal drug-resistant epilepsy is associated with both ictal and interictal ep...