U.S., Oct. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07857044) titled 'Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities' on March 29, 2023.
Brief Summary: Pulmonary vein isolation is an established intervention for atrial fibrillation. Patients with a paroxysmal atrial fibrillation have no or only few comorbidities and a good prognosis in respect to their atrial fibrillation. In contrast, patients with persistent atrial fibrillation often suffer from relevant comorbidities and recurrence of atrial fibrillation is common. Left-atrial fibrosis and its electrophysiological consequences are involved in the recurrence rate, but pathophysiological mechanisms are yet to be better ch...