U.S., Jan. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07351578) titled 'Knee Arthroplasty Recovery With Transcranial Direct Current Stimulation' on Jan. 09.
Brief Summary: Total knee arthroplasty (TKA) is widely performed to reduce pain from advanced osteoarthritis, yet many patients experience severe postoperative pain and up to 25-44% develop chronic postsurgical pain (CPSP). Transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique, has shown promise in reducing pain and opioid use in early studies but has not been evaluated using comprehensive perioperative, home-based protocols. This study will test whether a home-based tDCS intervention delivered before and after TKA...