U.S., Sept. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07800975) titled 'Keratoconus - Screening in Patients With Downs Syndrome' on April 28.
Brief Summary: The initial purpose of the study is to determine the true tomographic based age-specific prevalence of keratoconus among Danish patients with Downs Syndrome.
If, as expected, the prevalence is sizeable, the next step is to determine the optimal age for screening - considering both sensitivity and specificity as well as the need for early diagnosis in order to preserve a good visual acuity with glasses.
Lastly, the overall purpose based on the finding in the study is to evaluate if a tomographic screening program for keratoconus among patients with...