U.S., July 7 -- ClinicalTrials.gov registry received information related to the study (NCT07682636) titled 'Keloid Pathogenesis And Fibroblast Activation Study' on June 28.
Brief Summary: Keloids are benign fibroproliferative skin disorders characterized by excessive fibroblast activation and extracellular matrix deposition. The molecular mechanisms underlying keloid formation remain incompletely understood. This prospective observational study aims to investigate the biological characteristics of keloid tissue by comparing surgically resected keloid specimens with adjacent normal skin obtained from the same patients. Histological and molecular analyses, including histopathology, polymerase chain reaction (PCR), Western blotting, and relat...