Clinical Trial: iTBS Versus Standard 10 Hz rTMS for Treatment-Resistant Depression (TRD)

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07852065) titled 'iTBS Versus Standard 10 Hz rTMS for Treatment-Resistant Depression (TRD)' on Sept. 21.

Brief Summary: This randomised, parallel-group, non-inferiority trial compared intermittent theta burst stimulation (iTBS, 3-minute sessions) with standard 10 Hz repetitive transcranial magnetic stimulation (rTMS, 37-minute sessions) applied to the left dorsolateral prefrontal cortex (DLPFC) in adults with treatment-resistant depression (TRD). Participants received 20 sessions over 4 weeks. The primary aim was to determine whether iTBS is non-inferior to standard rTMS in reducing depressive symptoms (HDRS-17) at Week 4, and to compare patient-repor...