U.S., Jan. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07350772) titled 'It is an Observational Study That Compare Prognosis of Typical and Atypical Systemic Lupus Erythematosus Presentation' on Dec. 27, 2025.
Brief Summary: Atypical presentations of SLE including unusual initial symptoms, predominant organ involvement, late-onset disease and ANA-negative remain poorly characterized. These forms are often associated with delayed diagnosis and potentially worse clinical outcomes. Most existing studies focus on isolated rare manifestations rather than analyzing atypical SLE as a cohesive category. Understanding these differences is crucial and this study aims to compare atypical and typical SLE presentatio...