U.S., March 17 -- ClinicalTrials.gov registry received information related to the study (NCT07472348) titled 'Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors' on March 05.
Brief Summary: The objective of this observational study is to determine how frequently isoniazid (INH) causes liver injury (hepatotoxicity) in adults treated for tuberculosis (TB) or latent tuberculosis infection (LTBI) and to understand which factors increase this risk. The study also aims to describe how hepatotoxicity is managed in real-world clinical practice and whether treatments such as corticosteroids can improve liver function tests.
The main questions this study aims to answer are:
* How frequently does INH-induced hepatotoxic...