U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07540702) titled 'Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for Melasma' on April 14.
Brief Summary: Melasma is a chronic acquired hyperpigmentation disorder that commonly affects the face and has a significant impact on quality of life. Available treatments may improve pigmentation, but relapse is common and response can be variable.
This randomized split-face interventional study aims to compare the efficacy and safety of injectable platelet-rich fibrin (i-PRF) versus intradermal tranexamic acid (TA) in the treatment of facial melasma. Adult female patients with bilateral symmetrical facial melasma will be enrolled. In ea...