U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT07506993) titled 'Inflammation in Clear Aligners With and Without Attachments' on March 20.
Brief Summary: Problem: Clear aligner therapy is widely used in orthodontics due to improved periodontal outcomes compared to fixed appliances. However, composite attachments are frequently bonded to molars to enhance biomechanics, potentially creating plaque-retentive areas that may increase localized inflammatory responses. Currently, no studies have directly compared periodontal inflammatory biomarker levels in molars treated with clear aligners with versus without attachments. This gap limits understanding of the biological impact of attachments on periodo...