U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07850557) titled 'Hypertrophic Scar Prosthetic Pressure in Burn Amputee' on Sept. 18.
Brief Summary: Amputation following burn injury is rare but complex, affecting predominantly younger individuals with extensive burns, particularly electrical injuries, and often resulting in residual limbs characterized by scarring, contractures, grafted or flapped tissues, and heightened vulnerability to skin breakdown. Prosthesis-covered burn scars often appear to heal better than uncovered areas, suggesting a potential therapeutic pressure effect; however, excessive localized peak pressures may also contribute to recurrent wounds in grafted or scarred tissues. Th...