Clinical Trial: Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers

U.S., May 20 -- ClinicalTrials.gov registry received information related to the study (NCT07597213) titled 'Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers' on May 13.

Brief Summary: The goal of this clinical trial is to evaluate whether hyaluronic acid (HA) improves periodontal healing in people with periodontal disease who smoke. Moreover, the effects of HA on biomolecules and bacteria levels will be assesed during the follow up period.

The main questions it will answer are:

Will periodontal sites treated with HA gel after non-surgical periodontal treatment (NSPT) lead to better outcomes in clinical parameters compared to the sites treated with NSPT only in smokers?

Will adjunctive use of HA gel reduce oxi...