U.S., July 24 -- ClinicalTrials.gov registry received information related to the study (NCT07721272) titled 'Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation' on July 17.
Brief Summary: This is a research study to determine how COBENFY KarXT (FDA approved), a drug which has been approved for treatment of certain disorders, affects brain activity and cognitive tasks which may be regulated by the cholinergic system.
This study aims to answer: 1) how cholinergic circuitries act during task performance in humans, and 2) develop a better understanding of how cognitive control interacts with learning, memory and decision making in the setting of cholinergic manipulation.
Participants will complete a single treatment...