U.S., June 2 -- ClinicalTrials.gov registry received information related to the study (NCT07616297) titled 'Higher Radiation Dose to the Tumor May Help Avoid Surgery in Rectal Cancer Patients' on March 13.

Brief Summary: The goal of this prospective study is to evaluate if a higher radiation dose to the tumor can increase the organ preservation rate in non-locally advanced rectal cancer.

Study Start Date: Jan. 27

Study Type: INTERVENTIONAL

Condition: Rectal Cancer Radiation Oncology

Intervention: RADIATION: Simultaneous integrated boost to the tumor and positive mesorectal lymph nodes

Addition of a simultaneous integrated boost (SIB) to the standard chemoradiotherapy (CRT) scheme of 2.0 Gy to the mesorectum. The radiotherapy scheme ...