U.S., Aug. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07747805) titled 'GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD' on July 31.
Brief Summary: Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation, obesity-related metabolic dysfunction, skeletal muscle impairment, and progressive decline in lung function. While obesity has historically been viewed as protective in COPD, emerging evidence suggests that excess adiposity and adipokine dysregulation, particularly elevated leptin levels, contribute to chronic inflammation, impaired muscle function, and worse clinical outcomes. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have demonstrate...