U.S., Aug. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07746622) titled 'Gingival Graft vs T-PRF in Papilla Defects' on Aug. 13, 2025.
Brief Summary: Objective: Titanium-prepared platelet-rich fibrin (T-PRF) has emerged as a promising biomaterial in periodontal regenerative procedures. The aim of this study will be to compare the clinical effectiveness of de-epithelialized gingival grafts (DGG) and T-PRF in the reconstruction of deficient interdental papillae using the tunnel technique.
Methods: A total of 34 patients presenting with 115 Class I and II interdental papilla defects will be enrolled in this study. Interdental papilla reconstruction will be performed using the tunnel technique in combination...