Clinical Trial: FMT for 90-Day Outcome of Clinical Use in ICU Sepsis

U.S., June 27 -- ClinicalTrials.gov registry received information related to the study (NCT07670299) titled 'FMT for 90-Day Outcome of Clinical Use in ICU Sepsis' on June 19.

Brief Summary: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, representing one of the leading causes of death in intensive care units (ICUs) worldwide. Gut microbiota disruption is increasingly recognized as a key driver of persistent inflammation and multiple organ dysfunction in septic patients. Fecal microbiota transplantation (FMT) has emerged as a promising approach to restore gut microbial homeostasis. This study hypothesizes that FMT acts not through long-term engraftment of donor microbes, but via a "functio...