U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07224620) titled 'Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation' on Oct. 28.
Brief Summary: Patients with respiratory failure who require mechanical ventilation are not only at risk of death, but also of complications of prolonged ICU stay. Patients may have significant functional decline, impact in quality of life, develop psychiatric disorders and at long-term can lead to significant cost to society. Although sedation and analgesia are considered only supportive therapy, several studies have shown that in patients on mechanical ventilation, different approaches can have significant impact on patient centered outcomes. However, ...