Clinical Trial: Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism

U.S., Sept. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07824089) titled 'Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism' on Sept. 11.

Brief Summary: This randomized study will examine whether a 12-week supervised home-based endurance exercise program can reduce alcohol use and alcohol craving in adults with alcohol use disorder (AUD) and alcohol-related liver disease (ALD). Thirty participants will be assigned in a 1:1 ratio to endurance exercise plus standard of care or standard of care alone. Participants in the exercise group will cycle at home three days per week for approximately 60 minutes per session with remote supervision. The study will also e...