U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07750925) titled 'Examining Lithium's Mechanism in Bipolar Disorder' on June 16.

Brief Summary: The primary objective of the current study is to examine the acute effect of lithium on the visual and non-visual responses to light in a sample of healthy participants. Our experiments will investigate the effects of lithium on light sensitivity at the level of the retina as well as central visual and non-visual pathways.

Our primary hypothesis is that the administration of lithium to healthy volunteers will reduce the magnitude of a range of non-visual responses to light including melatonin suppression, alertness, performance, mood and electrophysiology ...