U.S., Sept. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07826091) titled 'Evaluation of the Aloe Vera Anti-inflammatory Effect on Apical Periodontitis.' on Sept. 05.

Brief Summary: The goal of this clinical trial is to evaluation aloe vera as intracanal medication anti-inflammatory also inter-appointment pain incidence compared with calcium hydroxide. The main questions it aims to answer are:

Does aloe vera reduced pro-inflammatory cytokine (IL-1b)? Researchers will compare aloe vera to calcium hydroxide intra-canal medication to see if it works to modulate the inflammatory response in necrotic teeth with apical periodontitis.

Participants will:

Receive the intra-canal medications following root canal...