U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07536659) titled 'Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals' on April 11.
Brief Summary: Physical exercise (walking and cycling) is a potent physiological stimulus that simultaneously alters energy balance, mechanical loading, and metabolic demands in the organism. Autophagy is recognized as a fundamental mechanism in the regulation of acute cellular responses to such stimuli, playing a critical role in maintaining cellular homeostasis, removing damaged proteins and organelles, and ensuring metabolic adaptation [1]. Experimental and translational studies have demonstrated that ...