U.S., April 17 -- ClinicalTrials.gov registry received information related to the study (NCT07532811) titled 'Evaluation of Perfusion and Ventilation Distribution in Children: a Pilot Study.' on March 18.
Brief Summary: Electrical impedance tomography (EIT) is a recent monitoring technique that provides information on regional ventilation distribution. Following the injection of a hypertonic saline bolus, EIT can also assess regional pulmonary perfusion distribution, allowing evaluation of the ventilation/perfusion (V/Q) ratio.
In adults, protocols for assessing perfusion distribution require the injection of 10 mL of a 7.5% or 10% NaCl solution or sodium bicarbonate over a few seconds. Studies have reported good hemodynamic tolerance, ad...