U.S., Jan. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07329634) titled 'Evaluation of Neoadjuvant Stereotactic Radiosurgery (SRS) and Multi-fraction SRS Alone for the Treatment of Large Brain Metastases' on Sept. 02, 2025.
Brief Summary: The prospective, two-arm, randomized, controlled, multicentric phase III RENESANS trial is designed to compare the efficacy and safety of neoadjuvant stereotactic radiosurgery (Neo-SRS) versus multi-fraction stereotactic radiosurgery (mfSRS) in patients with large brain metastases, with the primary objective of evaluating the incidence of central nervous system composite events.
Study Start Date: Jan., 2026
Study Type: INTERVENTIONAL
Condition:
Brain Metastasis
Int...