U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT07445828) titled 'Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome' on Jan. 29.
Brief Summary: Lynch syndrome is the most common hereditary cancer syndrome and is caused by pathogenic variants in DNA mismatch repair genes, resulting in a markedly increased lifetime risk of colorectal cancer. The estimated lifetime risk of colorectal cancer varies by the affected gene and is approximately 54-74% in men and 30-52% in women with Lynch syndrome. Colorectal cancer in this population is typically diagnosed at a younger age than in the general population. Current national guidelines recommend colonoscopic surveillance every one to two years...