U.S., April 14 -- ClinicalTrials.gov registry received information related to the study (NCT07526207) titled 'Estradiol 8 vs 12 mg for Endometrial Preparation in HRT-FET' on April 02.
Brief Summary: The goal of this clinical trial is to learn whether 12 mg or 8 mg of oral estradiol valerate is better for preparing the endometrium in women undergoing hormone replacement frozen embryo transfer (HRT-FET) cycles. It also aims to assess how these two doses affect pregnancy outcomes and cycle success.
The main questions it aims to answer are:
Does oral estradiol 12 mg/day improve the clinical pregnancy rate compared with 8 mg/day? Do the two doses differ in endometrial thickness, cycle cancellation, miscarriage, and embryo transfer outcomes?
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