Clinical Trial: Establishing a Controlled Human Infection Model for Influenza H3N2 as a Foundation for Pandemic Preparedness

U.S., Dec. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07305207) titled 'Establishing a Controlled Human Infection Model for Influenza H3N2 as a Foundation for Pandemic Preparedness' on Nov. 27.

Brief Summary: The overall objective is to establish an influenza Controlled Human Infection Model (CHIM) in Canada that can be used to assess the safety and efficacy of candidate vaccines, biologics, and therapeutics targeting influenza viruses.

Study Start Date: Feb. 01, 2026

Study Type: INTERVENTIONAL

Condition: Influenza (Healthy Volunteers)

Intervention: BIOLOGICAL: Intranasal inoculation of RG-A/Texas/71/2017 (H3N2) influenza in each naris on Day 1 of the study.

Participants will be inoculated intran...