U.S., Aug. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07146503) titled 'Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression' on Aug. 20.

Brief Summary: This observational study investigates the use of Esketamine Intranasal Spray in patients with Treatment-Resistant Depression in Real-World Settings. The study aims to evaluate the clinical outcomes, including efficacy and safety, of esketamine treatment. It also explores predictors of treatment response, focusing on biological pathways such as genetics, neuroimaging, and psychophysical measures. Additionally, the study examines how esketamine impacts patients' life functioning, including social and occupational aspects. The go...