U.S., June 27 -- ClinicalTrials.gov registry received information related to the study (NCT07670091) titled 'Endothelin Role In COronary Microcirculation' on June 19.
Brief Summary: Coronary microvascular dysfunction is an important cause of angina in patients who do not have significant blockages in the major coronary arteries. Previous studies suggest that endothelin-1, a naturally occurring substance that causes blood vessel constriction, may contribute to abnormalities in the coronary microcirculation.
The ERICOM study aims to investigate whether treatment with bosentan, an endothelin receptor antagonist, can improve coronary microvascular function in patients with angina and evidence of coronary microvascular dysfunction. Participant...