U.S., Aug. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07137364) titled 'Efficacy of Spironolactone Combined With Antihypertensive Drugs in Patients With Primary Aldosteronism' on Aug. 03.
Brief Summary: The goal of this observational study is to learn about the optimal dose of spironolactone treatment and the long-term outcomes on cardiovascular and cerebrovascular events in patients with lateralized PA who are unwilling to undergo surgery. The main question it aims to answer is:
1. What is the long-term effect of spironolactone treatment for lateralized PA?
2. What is the optimal dose of spironolactone treatment for the relief of renin inhibition in patients with lateralized PA? Participants will rec...