U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07539298) titled 'Effects of VALsartan On atRIAl Mitral Regurgitation: A Pilot Randomized Controlled Trial' on April 13.

Brief Summary: The goal of this clinical trial is to learn whether valsartan can slow the progression of atrial functional mitral regurgitation (AFMR) in adults with preserved left ventricular ejection fraction. The study will also evaluate the safety and tolerability of valsartan in this population.

The main questions it aims to answer are:

* Does treatment with valsartan reduce the progression of atrial functional mitral regurgitation compared with placebo?

* Does valsartan have favorable effects on mitral valve leaflet remod...