Clinical Trial: Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity

U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07893457) titled 'Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity' on Oct. 09.

Brief Summary: This study will assess whether a single subcutaneous dose of tirzepatide 7.5 mg , compared with saline placebo, increases total esophageal acid exposure time during a 96-hour wireless pH recording beginning about 48 hours after study medication.

Study Start Date: Oct. 26

Study Type: INTERVENTIONAL

Condition: Obese Adults

Intervention: DRUG: Placebo

Placebo subcutaneously once

DRUG: Tirzepatide

tirzepatide 7.5 mg subcutaneously once

Recruitment Status: NOT_YET_RECRUITING

Spo...