U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07497347) titled 'Effects of Specific Amino Acid Supplementation and Lifestyle Factors on Brain Ageing' on Feb. 09.

Brief Summary: The aim of this clinical trial is to investigate the effects of L-serine supplementation on cognitive decline and psychosocial functioning in older adults with late-life depression (LLD). The study will evaluate changes in depressive symptoms, neural and cognitive functioning, and will assess neurophysiological, metagenomic, and biochemical alterations associated with L-serine supplementation compared with placebo.

The main research questions are:

* Does L-serine supplementation affect cognitive function, depressive sy...